fi - Glucosidase Activity in the Rat Small Intestine toward Quercetin
نویسنده
چکیده
with the quercetin monoglucosides, quercetin-3-O-fi-Dglucopyranoside (Q3G), quercetin-4'-O-fi-D-glucopyranoside (Q4'G) and quercetin-7-O:t7-D-glucopyranoside (Q7G), as well as with quercetin-3-O-rutinoside (rutin) and pnitrophenyl-ll-D-gl"cepyranoside (NPG) by using the HPLC technique. Enzymes were prepared from rat small intestinal mucosa of the duodenum, jejunum and ilellm, among which the enzyme activity of the jejunllm was
منابع مشابه
Microsomal quercetin glucuronidation in rat small intestine depends on age and segment.
UDP-glucuronosyltransferase (UGT) activity toward the flavonoid quercetin and UGT protein were characterized in three equidistant small intestine (SI) segments from 4-, 12-, 18-, and 28-month-old male Fischer 344 rats (n = 8/age) using villin to control for enterocyte content. SI microsomal intrinsic clearance of quercetin was increased 3- to 9-fold from 4 months in the proximal and distal SI a...
متن کاملEffects of Onion (Allium cepa L.) Extract Administration on Intestinal α-Glucosidases Activities and Spikes in Postprandial Blood Glucose Levels in SD Rats Model
Diets high in calories and sweetened foods with disaccharides frequently lead to exaggerated postprandial spikes in blood glucose. This state induces immediate oxidant stress and free radicals which trigger oxidative stress-linked diabetic complications. One of the therapeutic approaches for decreasing postprandial hyperglycemia is to retard absorption of glucose by the inhibition of carbohydra...
متن کاملQuercetin attenuates fasting and postprandial hyperglycemia in animal models of diabetes mellitus
The objective of this study was to investigate the hypoglycemic effects of quercetin (QE) in animal models of diabetes mellitus (DM). A starch solution (1 g/kg) with and without QE (100 mg/kg) or acarbose (40 mg/kg) was orally administered to streptozotocin (STZ)-induced diabetic rats after an overnight fast. Postprandial plasma glucose levels were measured and incremental areas under the respo...
متن کاملEffect of Phenobarbital on Chloramphonicol-Induced Toxicity in Rat Liver and Small Intestine
Objective(s): The aim of the present study is to determine the effect of Chloramphenicol (CAP) on rat liver and small intestine. Effect of phenobarbital (PB) on CAP toxicity was also investigated. Materials and Methods: Rats were received CAP at doses of 0, 200, 400 and 600 mg/kg. Another group was pretreated with 80 mg/kg PB 30 min prior to administration of various doses...
متن کاملThe Effect of Prolonged Exposure to Low-Frequency Electromagnetic Fields on the Cholinergic System in the Small Intestine of Male Rat
Background & Aims: In the recent years, increasing rate of using electronic devices which generate electromagnetic fields , has caused researchers, attention to the effects of electromagnetic fields on human health. The aim of this study is to investigate the effect of prolonged exposure to extremely low frequency electromagnetic fields(ELF) on the Cholinergic system in the small intestine of r...
متن کامل